CD200 as a Valuable Marker for Differentiating between CLL and Other B-cell Lymph Proliferative Disorders

Chronic lymphocytic leukaemia (CLL) being the commonest subtype of mature B-cell lymphoid neoplasms need to be differentiated correctly from other B-chronic lymphoproliferative disorders (BCLPD). CD200 is an essential marker for prognosis and diagnosis CLL. Sixty patients diagnosed with BCLPD were evaluated expression eight-colour flow cytometry. An integration modified Matutes score applied CLL diagnosis. The overall immunophenotype in this study showed significant, frequent CD5, CD22, CD23, CD43 CD200. Atypical versus typical patients’ phenotype comparison revealed significant lower CD5 higher CD79b atypical patients. was expressed significantly (typical atypical) than MCL who dim only twenty-five percent inclusion within diagnostic markers can empower accuracy